Taxol (Paclitaxel)

Paclitaxel, produced by the Pacific yew tree (Taxus brevifolia) as a natural anti-herbivore/anti-fungal chemical defense compound. Wani, Taylor, Wall, Coggon & McPhail, "Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia" (J. Am. Chem. Soc. 93, 2325-2327, 1971-05-01, OpenAlex W2037490361, 4,088 citations). Became one of the most widely used chemotherapy agents (breast, ovarian, lung cancer) and remains first-line decades after approval; billions of dollars in cumulative sales. Classified under Chemistry/Biochemistry, not Biology, matching the statins/cyclosporine nodes above.